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Target
Neuropeptide Y receptor type 1
Ligand
BDBM42443
Substrate
n/a
Meas. Tech.
Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1)
IC50
6837±n/a nM
Citation
 PubChem, PC Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1) PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42443
Synonyms:
2-(cyclohexylamino)-1-(2,2,4,7-tetramethyl-1-quinolinyl)ethanone;oxalic acid | 2-(cyclohexylamino)-1-(2,2,4,7-tetramethyl-1-quinolyl)ethanone;oxalic acid | 2-(cyclohexylamino)-1-(2,2,4,7-tetramethylquinolin-1-yl)ethanone;ethanedioic acid | 2-(cyclohexylamino)-1-(2,2,4,7-tetramethylquinolin-1-yl)ethanone;oxalic acid | MLS000709785 | SMR000286952 | cid_16189737
Type:
Small organic molecule
Emp. Form.:
C21H30N2O
Mol. Mass.:
326.4757
SMILES:
CC1=CC(C)(C)N(C(=O)CNC2CCCCC2)c2cc(C)ccc12 |t:1|
Structure:
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