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Target
Neuropeptide Y receptor type 1
Ligand
BDBM42456
Substrate
n/a
Meas. Tech.
Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1)
IC50
3648±n/a nM
Citation
 PubChem, PC Dose response cell-based screening assay for antagonists of neuropeptide Y receptor Y1 (NPY-Y1) PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42456
Synonyms:
3-(2,4-dimethylphenyl)-2-phenyl-4,5-dihydroimidazo[1,2-a]quinolin-10-ium;bromide | MLS001007136 | SMR000352439 | cid_16196151
Type:
Small organic molecule
Emp. Form.:
C25H23N2
Mol. Mass.:
351.463
SMILES:
Cc1ccc(c(C)c1)-n1c(c[n+]-2c1CCc1ccccc-21)-c1ccccc1 |(4.56,4.78,;5.04,6.24,;4.01,7.39,;4.49,8.85,;6,9.17,;7.02,8.03,;8.53,8.34,;6.55,6.56,;6.47,10.64,;5.57,11.88,;6.47,13.11,;7.93,12.65,;7.93,11.11,;9.26,10.34,;10.6,11.11,;10.6,12.65,;12,13.43,;12.01,15.03,;10.62,15.83,;9.24,15.02,;9.26,13.42,;4.03,11.88,;3.26,13.21,;1.72,13.21,;.95,11.88,;1.72,10.54,;3.26,10.54,)|
Structure:
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