Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM42438
Substrate
n/a
Meas. Tech.
Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism
IC50
29590±n/a nM
Citation
 PubChem, PC Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM42438
Synonyms:
(2Z)-3-ethyl-2-[[3-methyl-5-(2-methylphenyl)-1,3-thiazol-3-ium-2-yl]methylidene]-1,3-benzothiazole;iodide | (2Z)-3-ethyl-2-[[3-methyl-5-(2-methylphenyl)-2-thiazol-3-iumyl]methylidene]-1,3-benzothiazole;iodide | (2Z)-3-ethyl-2-[[3-methyl-5-(o-tolyl)thiazol-3-ium-2-yl]methylene]-1,3-benzothiazole;iodide | 3-ethyl-2-{(Z)-[3-methyl-5-(2-methylphenyl)-1,3-thiazol-2(3H)-ylidene]methyl}-1,3-benzothiazol-3-ium | MLS000727848 | SMR000306545 | cid_16188793
Type:
Small organic molecule
Emp. Form.:
C21H21N2S2
Mol. Mass.:
365.534
SMILES:
CCN1\C(Sc2ccccc12)=C\c1sc(c[n+]1C)-c1ccccc1C
Structure:
Search PDB for entries with ligand similarity: