Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM42441
Substrate
n/a
Meas. Tech.
Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism
IC50
>35000±n/a nM
Citation
 PubChem, PC Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM42441
Synonyms:
2-(4-methoxyphenyl)-N-(3-nitroanilino)-2-oxoethanimidoyl cyanide | 2-({3-nitrophenyl}hydrazono)-3-(4-methoxyphenyl)-3-oxopropanenitrile | 3-(4-methoxyphenyl)-2-[(3-nitrophenyl)hydrazinylidene]-3-oxidanylidene-propanenitrile | 3-(4-methoxyphenyl)-2-[(3-nitrophenyl)hydrazinylidene]-3-oxopropanenitrile | 3-keto-3-(4-methoxyphenyl)-2-[(3-nitrophenyl)hydrazono]propionitrile | MLS000702639 | SMR000225416 | cid_830586
Type:
Small organic molecule
Emp. Form.:
C16H12N4O4
Mol. Mass.:
324.2909
SMILES:
COc1ccc(cc1)C(=O)[C-](\N=[NH+]\c1cccc(c1)[N+]([O-])=O)C#N
Structure:
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