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Target
Neuropeptide Y receptor type 2
Ligand
BDBM42449
Substrate
n/a
Meas. Tech.
Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism
IC50
4436±n/a nM
Citation
 PubChem, PC Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM42449
Synonyms:
3-fluoranyl-N-[2-[(3,6,7-trimethylquinolin-2-yl)amino]ethyl]benzamide | 3-fluoro-N-[2-[(3,6,7-trimethyl-2-quinolinyl)amino]ethyl]benzamide | 3-fluoro-N-[2-[(3,6,7-trimethyl-2-quinolyl)amino]ethyl]benzamide | 3-fluoro-N-[2-[(3,6,7-trimethylquinolin-2-yl)amino]ethyl]benzamide | MLS000688426 | SMR000284362 | cid_3206677
Type:
Small organic molecule
Emp. Form.:
C21H22FN3O
Mol. Mass.:
351.4173
SMILES:
Cc1cc2cc(C)c(NCCNC(=O)c3cccc(F)c3)nc2cc1C
Structure:
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