Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM42461
Substrate
n/a
Meas. Tech.
Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism
IC50
>35000±n/a nM
Citation
 PubChem, PC Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM42461
Synonyms:
3-[(4-methoxyphenyl)-methyl-sulfamoyl]-N-(4-methylcyclohexyl)benzamide | 3-[(4-methoxyphenyl)-methylsulfamoyl]-N-(4-methylcyclohexyl)benzamide | MLS000760815 | SMR000370909 | cid_16196679
Type:
Small organic molecule
Emp. Form.:
C22H28N2O4S
Mol. Mass.:
416.534
SMILES:
COc1ccc(cc1)N(C)S(=O)(=O)c1cccc(c1)C(=O)NC1CCC(C)CC1 |(16.42,7.7,;16.42,6.16,;15.08,5.39,;15.08,3.85,;13.75,3.08,;12.42,3.85,;12.42,5.39,;13.75,6.16,;11.08,3.08,;9.75,3.85,;11.08,1.54,;12.62,1.54,;9.54,1.54,;11.08,,;12.42,-.77,;12.42,-2.31,;11.08,-3.08,;9.75,-2.31,;9.75,-.77,;8.41,-3.08,;7.08,-2.31,;8.41,-4.62,;7.08,-5.39,;7.08,-6.93,;5.75,-7.7,;4.41,-6.93,;3.08,-7.7,;4.41,-5.39,;5.75,-4.62,)|
Structure:
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