Target
Neuropeptide Y receptor type 1
Ligand
BDBM42472
Substrate
n/a
Meas. Tech.
Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism
IC50
5546±n/a nM
Citation
 PubChem, PC Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42472
Synonyms:
4-(2-methylpropoxy)benzoic acid [5-[(dimethylamino)methyl]-2,2-dimethyl-4-oxanyl] ester;hydrochloride | 4-isobutoxybenzoic acid [5-[(dimethylamino)methyl]-2,2-dimethyl-tetrahydropyran-4-yl] ester;hydrochloride | MLS000080839 | SMR000046315 | [5-[(dimethylamino)methyl]-2,2-dimethyl-oxan-4-yl] 4-(2-methylpropoxy)benzoate;hydrochloride | [5-[(dimethylamino)methyl]-2,2-dimethyloxan-4-yl] 4-(2-methylpropoxy)benzoate;hydrochloride | cid_6603250
Type:
Small organic molecule
Emp. Form.:
C21H33NO4
Mol. Mass.:
363.491
SMILES:
CC(C)COc1ccc(cc1)C(=O)OC1CC(C)(C)OCC1CN(C)C
Structure:
Search PDB for entries with ligand similarity: