Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM42477
Substrate
n/a
Meas. Tech.
Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism
IC50
7156±n/a nM
Citation
 PubChem, PC Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42477
Synonyms:
MLS000047576 | N-(1,3-benzodioxol-5-yl)-3-(4-methoxyphenyl)-4-oxidanylidene-phthalazine-1-carboxamide | N-(1,3-benzodioxol-5-yl)-3-(4-methoxyphenyl)-4-oxo-1-phthalazinecarboxamide | N-(1,3-benzodioxol-5-yl)-3-(4-methoxyphenyl)-4-oxophthalazine-1-carboxamide | N-(1,3-benzodioxol-5-yl)-4-keto-3-(4-methoxyphenyl)phthalazine-1-carboxamide | N-1,3-benzodioxol-5-yl-3-(4-methoxyphenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide | SMR000033587 | cid_3235942
Type:
Small organic molecule
Emp. Form.:
C23H17N3O5
Mol. Mass.:
415.3982
SMILES:
COc1ccc(cc1)-n1nc(C(=O)Nc2ccc3OCOc3c2)c2ccccc2c1=O
Structure:
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