Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM42496
Substrate
n/a
Meas. Tech.
Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism
IC50
>35000±n/a nM
Citation
 PubChem, PC Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42496
Synonyms:
1-(3-methylphenyl)-3-[(phenylmethyl)carbamothioylamino]thiourea | 1-[[(3-methylanilino)-sulfanylidenemethyl]amino]-3-(phenylmethyl)thiourea | 1-benzyl-3-(m-tolylthiocarbamoylamino)thiourea | 1-benzyl-3-[(3-methylphenyl)carbamothioylamino]thiourea | MLS000537697 | N-benzyl-N'-(3-methylphenyl)-1,2-hydrazinedicarbothioamide | SMR000143934 | cid_971947
Type:
Small organic molecule
Emp. Form.:
C16H18N4S2
Mol. Mass.:
330.471
SMILES:
Cc1cccc(NC(=S)NNC(=S)NCc2ccccc2)c1
Structure:
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