Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM42557
Substrate
n/a
Meas. Tech.
Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism
IC50
6127±n/a nM
Citation
 PubChem, PC Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM42557
Synonyms:
(E)-3-(4-chlorophenyl)-2-propenoic acid [2-oxo-2-(2-phenylanilino)ethyl] ester | (E)-3-(4-chlorophenyl)acrylic acid [2-keto-2-(2-phenylanilino)ethyl] ester | MLS000409048 | SMR000264080 | [2-oxidanylidene-2-[(2-phenylphenyl)amino]ethyl] (E)-3-(4-chlorophenyl)prop-2-enoate | [2-oxo-2-(2-phenylanilino)ethyl] (E)-3-(4-chlorophenyl)prop-2-enoate | cid_2446403
Type:
Small organic molecule
Emp. Form.:
C23H18ClNO3
Mol. Mass.:
391.847
SMILES:
Clc1ccc(\C=C\C(=O)OCC(=O)Nc2ccccc2-c2ccccc2)cc1
Structure:
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