Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM43234
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
EC50
6400±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM43234
Synonyms:
2-[(4-chloranylphenoxy)methyl]-5-methoxy-1-benzofuran-3-carboxylic acid | 2-[(4-chlorophenoxy)methyl]-5-methoxy-1-benzofuran-3-carboxylic acid | 2-[(4-chlorophenoxy)methyl]-5-methoxy-3-benzofurancarboxylic acid | 2-[(4-chlorophenoxy)methyl]-5-methoxy-benzofuran-3-carboxylic acid | UNM000011078301 | cid_1502918
Type:
Small organic molecule
Emp. Form.:
C17H13ClO5
Mol. Mass.:
332.735
SMILES:
COc1ccc2oc(COc3ccc(Cl)cc3)c(C(O)=O)c2c1
Structure:
Search PDB for entries with ligand similarity: