Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM43239
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
EC50
989±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM43239
Synonyms:
3-(4-acetylphenyl)-1-(4-nitrophenyl)-2-propyn-1-one | 3-(4-acetylphenyl)-1-(4-nitrophenyl)prop-2-yn-1-one | 3-(4-ethanoylphenyl)-1-(4-nitrophenyl)prop-2-yn-1-one | UNM000011086101 | cid_25109927
Type:
Small organic molecule
Emp. Form.:
C17H11NO4
Mol. Mass.:
293.2735
SMILES:
CC(=O)c1ccc(cc1)C#CC(=O)c1ccc(cc1)[N+]([O-])=O
Structure:
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