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Target
Cell division control protein 42 homolog
Ligand
BDBM43241
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
EC50
358±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM43241
Synonyms:
1-[2-(2,5-dimethylphenoxy)ethyl]-3-indolecarboxylic acid | 1-[2-(2,5-dimethylphenoxy)ethyl]indole-3-carboxylic acid | ML098 | UNM-0000305818 | cid_7345532
Type:
Small organic molecule
Emp. Form.:
C19H19NO3
Mol. Mass.:
309.3591
SMILES:
Cc1ccc(C)c(OCCn2cc(C(O)=O)c3ccccc23)c1
Structure:
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