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Target
GTPase KRas [1-37]
Ligand
BDBM43251
Substrate
n/a
Meas. Tech.
Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
EC50
78.16±n/a nM
Citation
 PubChem, PC Multiplexed dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM43251
Synonyms:
5-[[(2-chlorobenzyl)amino]methyl]-4-methyl-2-thenoic acid | 5-[[(2-chlorophenyl)methylamino]methyl]-4-methyl-2-thiophenecarboxylic acid | 5-[[(2-chlorophenyl)methylamino]methyl]-4-methyl-thiophene-2-carboxylic acid | 5-[[(2-chlorophenyl)methylamino]methyl]-4-methylthiophene-2-carboxylic acid | UNM000011080001 | cid_20890249
Type:
Small organic molecule
Emp. Form.:
C14H14ClNO2S
Mol. Mass.:
295.784
SMILES:
Cc1cc(sc1CNCc1ccccc1Cl)C(O)=O
Structure:
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