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Target
Ras-related protein Rab-2A
Ligand
BDBM43255
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
EC50
26290±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related protein Rab-2A
Synonyms:
RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A.
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23545.28
Organism:
Canis lupus familiaris
Description:
gi_46577642
Residue:
212
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
  
Inhibitor
Name:
BDBM43255
Synonyms:
1-(3,6-dichloro-9-carbazolyl)-3-[2-(3H-indol-3-yl)ethylamino]-2-propanol | 1-(3,6-dichloro-9H-carbazol-9-yl)-3-{[2-(3H-indol-3-yl)ethyl]amino}-2-propanol | 1-(3,6-dichlorocarbazol-9-yl)-3-[2-(3H-indol-3-yl)ethylamino]propan-2-ol | 1-[3,6-bis(chloranyl)carbazol-9-yl]-3-[2-(3H-indol-3-yl)ethylamino]propan-2-ol | MLS000698923 | SMR000229826 | cid_15944990
Type:
Small organic molecule
Emp. Form.:
C25H23Cl2N3O
Mol. Mass.:
452.376
SMILES:
OC(CNCCc1c[nH]c2ccccc12)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc12
Structure:
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