Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43267
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
55440±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43267
Synonyms:
3,5-Dihydroxy-benzoic acid (4-methylsulfanyl-benzylidene)-hydrazide | 3,5-dihydroxy-N-[(4-methylsulfanylphenyl)methylideneamino]benzamide | 3,5-dihydroxy-N-[[4-(methylthio)benzylidene]amino]benzamide | 3,5-dihydroxy-N-[[4-(methylthio)phenyl]methylideneamino]benzamide | MLS000553612 | N-[(4-methylsulfanylphenyl)methylideneamino]-3,5-bis(oxidanyl)benzamide | SMR000171545 | cid_769767
Type:
Small organic molecule
Emp. Form.:
C15H14N2O3S
Mol. Mass.:
302.348
SMILES:
CSc1ccc(C=NNC(=O)c2cc(O)cc(O)c2)cc1 |w:7.7|
Structure:
Search PDB for entries with ligand similarity: