Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43272
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
22100±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43272
Synonyms:
4-chloranyl-2-[(4-methoxyphenyl)carbonylamino]benzoic acid | 4-chloro-2-(p-anisoylamino)benzoic acid | 4-chloro-2-[(4-methoxybenzoyl)amino]benzoic acid | 4-chloro-2-[[(4-methoxyphenyl)-oxomethyl]amino]benzoic acid | MLS000663391 | SMR000300965 | cid_1254149
Type:
Small organic molecule
Emp. Form.:
C15H12ClNO4
Mol. Mass.:
305.713
SMILES:
COc1ccc(cc1)C(=O)Nc1cc(Cl)ccc1C(O)=O
Structure:
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