Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43279
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
25940±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43279
Synonyms:
5-[(m-anisylamino)methyl]-4-methyl-2-thenoic acid | 5-[[(3-methoxyphenyl)methylamino]methyl]-4-methyl-2-thiophenecarboxylic acid | 5-[[(3-methoxyphenyl)methylamino]methyl]-4-methyl-thiophene-2-carboxylic acid | 5-[[(3-methoxyphenyl)methylamino]methyl]-4-methylthiophene-2-carboxylic acid | UNM000011080201 | cid_20890254
Type:
Small organic molecule
Emp. Form.:
C15H17NO3S
Mol. Mass.:
291.365
SMILES:
COc1cccc(CNCc2sc(cc2C)C(O)=O)c1
Structure:
Search PDB for entries with ligand similarity: