Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM43282
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant
EC50
2186±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM43282
Synonyms:
5-[(5-chloro-2-methoxy-anilino)methyl]-4-methyl-2-thenoic acid | 5-[(5-chloro-2-methoxyanilino)methyl]-4-methyl-2-thiophenecarboxylic acid | 5-[(5-chloro-2-methoxyanilino)methyl]-4-methylthiophene-2-carboxylic acid | 5-[[(5-chloranyl-2-methoxy-phenyl)amino]methyl]-4-methyl-thiophene-2-carboxylic acid | UNM000011081701 | cid_20899532
Type:
Small organic molecule
Emp. Form.:
C14H14ClNO3S
Mol. Mass.:
311.784
SMILES:
COc1ccc(Cl)cc1NCc1sc(cc1C)C(O)=O
Structure:
Search PDB for entries with ligand similarity: