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Target
Cyclin-dependent kinase 7
Ligand
BDBM32359
Substrate
n/a
Meas. Tech.
CDK7 counterscreen of confirmed PKD inhibitors-57K library addition
IC50
>100000±n/a nM
Citation
 PubChem, PC CDK7 counterscreen of confirmed PKD inhibitors-57K library addition PubChem Bioassay (2008)[AID] 
Target
Name:
Cyclin-dependent kinase 7
Synonyms:
39 kDa protein kinase | CAK | CAK1 | CDK-activating kinase | CDK-activating kinase 1 (CAK) | CDK7 | CDK7_HUMAN | CDKN7 | Cell division protein kinase 7 | Cyclin-Dependent Kinase 7 (CDK7) | Cyclin-dependent kinase 7 (CDK7/cyclin H) | MO15 | P39 Mo15 | STK1 | TFIIH basal transcription factor complex kinase subunit
Type:
Enzyme Subunit
Mol. Mass.:
39047.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
346
Sequence:
MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
  
Inhibitor
Name:
BDBM32359
Synonyms:
MLS000772778 | N-(2-naphthalenyl)-2-(pyridin-4-ylthio)acetamide | N-(2-naphthyl)-2-(4-pyridylthio)acetamide | N-naphthalen-2-yl-2-pyridin-4-ylsulfanyl-ethanamide | N-naphthalen-2-yl-2-pyridin-4-ylsulfanylacetamide | SMR000377376 | cid_2103808
Type:
Small organic molecule
Emp. Form.:
C17H14N2OS
Mol. Mass.:
294.371
SMILES:
O=C(CSc1ccncc1)Nc1ccc2ccccc2c1
Structure:
Search PDB for entries with ligand similarity: