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Target
Serine/threonine-protein kinase PLK1
Ligand
BDBM32339
Substrate
n/a
Meas. Tech.
PLK1 counterscreening assay for identified PKD inhibitors
IC50
>50000±n/a nM
Citation
 PubChem, PC PLK1 counterscreening assay for identified PKD inhibitors PubChem Bioassay (2008)[AID] 
Target
Name:
Serine/threonine-protein kinase PLK1
Synonyms:
PLK | PLK-1 | PLK1 | PLK1_HUMAN | Polo-like kinase 1 (PlK1) | Polo-like kinase 1 (Plk-1) | STPK13 | Serine/threonine-protein kinase (PLK1) | Serine/threonine-protein kinase 13 | polo-like kinase
Type:
Serine/threonine-protein kinase
Mol. Mass.:
68277.16
Organism:
Homo sapiens (Human)
Description:
P53350
Residue:
603
Sequence:
MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS
  
Inhibitor
Name:
BDBM32339
Synonyms:
5-Bromo-furan-2-carboxylic acid [2-(4-methanesulfonyl-piperazin-1-yl)-phenyl]-amide | 5-bromanyl-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]furan-2-carboxamide | 5-bromo-N-[2-(4-mesylpiperazino)phenyl]-2-furamide | 5-bromo-N-[2-(4-methylsulfonyl-1-piperazinyl)phenyl]-2-furancarboxamide | 5-bromo-N-[2-(4-methylsulfonylpiperazin-1-yl)phenyl]furan-2-carboxamide | MLS000123947 | SMR000124483 | cid_979832
Type:
Small organic molecule
Emp. Form.:
C16H18BrN3O4S
Mol. Mass.:
428.301
SMILES:
CS(=O)(=O)N1CCN(CC1)c1ccccc1NC(=O)c1ccc(Br)o1
Structure:
Search PDB for entries with ligand similarity: