Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43547
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
5095±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43547
Synonyms:
(3-Cyano-2-methyl-indol-1-yl)-acetic acid | 2-(3-cyano-2-methyl-1-indolyl)acetic acid | 2-(3-cyano-2-methyl-indol-1-yl)acetic acid | 2-(3-cyano-2-methyl-indol-1-yl)ethanoic acid | 2-(3-cyano-2-methylindol-1-yl)acetic acid | MLS000075634 | SMR000013849 | cid_653215
Type:
Small organic molecule
Emp. Form.:
C12H10N2O2
Mol. Mass.:
214.22
SMILES:
Cc1c(C#N)c2ccccc2n1CC(O)=O
Structure:
Search PDB for entries with ligand similarity: