Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43552
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43552
Synonyms:
MLS000027654 | N-(1H-indol-3-ylmethyl)-N-methyl-1-phenyl-methanamine | N-(1H-indol-3-ylmethyl)-N-methyl-1-phenylmethanamine | SMR000034986 | benzyl-(1H-indol-3-ylmethyl)-methyl-amine | cid_659062
Type:
Small organic molecule
Emp. Form.:
C17H18N2
Mol. Mass.:
250.3382
SMILES:
CN(Cc1c[nH]c2ccccc12)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: