Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43583
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
1357±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43583
Synonyms:
4-(3,4-dihydro-2H-quinolin-1-yl)-[1,2,4]triazolo[4,3-a]quinoxaline | MLS000119008 | SMR000095947 | cid_5307993
Type:
Small organic molecule
Emp. Form.:
C18H15N5
Mol. Mass.:
301.3452
SMILES:
C1CN(c2ccccc2C1)c1nc2ccccc2n2cnnc12
Structure:
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