Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43586
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
27850±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43586
Synonyms:
3-(4-chlorophenyl)-1-methyl-N-(3-morpholin-4-ylpropyl)thieno[2,3-c]pyrazole-5-carboxamide | 3-(4-chlorophenyl)-1-methyl-N-(3-morpholinopropyl)thieno[2,3-c]pyrazole-5-carboxamide | 3-(4-chlorophenyl)-1-methyl-N-[3-(4-morpholinyl)propyl]-5-thieno[2,3-c]pyrazolecarboxamide | MLS000117282 | SMR000094232 | cid_5308340
Type:
Small organic molecule
Emp. Form.:
C20H23ClN4O2S
Mol. Mass.:
418.94
SMILES:
Cn1nc(-c2ccc(Cl)cc2)c2cc(sc12)C(=O)NCCCN1CCOCC1
Structure:
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