Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43601
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
6131±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43601
Synonyms:
1-(3-bromo-4-methoxy-benzyl)-4-tosyl-piperazine | 1-(3-bromo-4-methoxybenzyl)-4-[(4-methylphenyl)sulfonyl]piperazine | 1-[(3-bromanyl-4-methoxy-phenyl)methyl]-4-(4-methylphenyl)sulfonyl-piperazine | 1-[(3-bromo-4-methoxyphenyl)methyl]-4-(4-methylphenyl)sulfonylpiperazine | MLS000530544 | SMR000135524 | cid_1360988
Type:
Small organic molecule
Emp. Form.:
C19H23BrN2O3S
Mol. Mass.:
439.367
SMILES:
COc1ccc(CN2CCN(CC2)S(=O)(=O)c2ccc(C)cc2)cc1Br
Structure:
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