Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43610
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
7746±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43610
Synonyms:
(E)-3-(2-nitrophenyl)-2-propenoic acid [2-(dimethylamino)-2-oxoethyl] ester | (E)-3-(2-nitrophenyl)acrylic acid [2-(dimethylamino)-2-keto-ethyl] ester | MLS000564263 | SMR000151831 | [2-(dimethylamino)-2-oxidanylidene-ethyl] (E)-3-(2-nitrophenyl)prop-2-enoate | [2-(dimethylamino)-2-oxoethyl] (E)-3-(2-nitrophenyl)prop-2-enoate | cid_2445886
Type:
Small organic molecule
Emp. Form.:
C13H14N2O5
Mol. Mass.:
278.2607
SMILES:
CN(C)C(=O)COC(=O)\C=C\c1ccccc1[N+]([O-])=O
Structure:
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