Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43615
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
3325±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43615
Synonyms:
2-(2-keto-4-methyl-pyrimid[1,2-b]indazol-6-yl)-N-propyl-acetamide | 2-(4-methyl-2-oxidanylidene-pyrimido[1,2-b]indazol-6-yl)-N-propyl-ethanamide | 2-(4-methyl-2-oxo-6-pyrimido[1,2-b]indazolyl)-N-propylacetamide | 2-(4-methyl-2-oxopyrimido[1,2-b]indazol-6-yl)-N-propylacetamide | MLS000522787 | SMR000128053 | cid_3249106
Type:
Small organic molecule
Emp. Form.:
C16H18N4O2
Mol. Mass.:
298.3397
SMILES:
CCCNC(=O)Cn1c2ccccc2c2nc(=O)cc(C)n12
Structure:
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