Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43618
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
468±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43618
Synonyms:
3-methyl-N-[(4-phenyl-1,3-thiazol-2-yl)carbamothioyl]butanamide | 3-methyl-N-[(4-phenylthiazol-2-yl)thiocarbamoyl]butyramide | 3-methyl-N-[[(4-phenyl-2-thiazolyl)amino]-sulfanylidenemethyl]butanamide | 3-methyl-N-{[(4-phenyl-1,3-thiazol-2-yl)amino]carbonothioyl}butanamide | MLS000573915 | SMR000195502 | cid_823806
Type:
Small organic molecule
Emp. Form.:
C15H17N3OS2
Mol. Mass.:
319.445
SMILES:
CC(C)CC(=O)NC(=S)Nc1nc(cs1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: