Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43620
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43620
Synonyms:
(2E)-2-(1,3-benzothiazol-2-yl)-2-(2-ketoindolin-3-ylidene)acetonitrile | (2E)-2-(1,3-benzothiazol-2-yl)-2-(2-oxidanylidene-1H-indol-3-ylidene)ethanenitrile | (2E)-2-(1,3-benzothiazol-2-yl)-2-(2-oxo-1H-indol-3-ylidene)acetonitrile | MLS000418391 | SMR000264930 | cid_5779525
Type:
Small organic molecule
Emp. Form.:
C17H9N3OS
Mol. Mass.:
303.338
SMILES:
O=C1Nc2ccccc2\C1=C(\C#N)c1nc2ccccc2s1
Structure:
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