Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43628
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>6190±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43628
Synonyms:
4-(1-isobutyl-1,3,4,9-tetrahydro-2H-beta-carbolin-2-yl)-N,N-dimethyl-4-oxobutanamide | 4-(1-isobutyl-1,3,4,9-tetrahydro-beta-carbolin-2-yl)-4-keto-N,N-dimethyl-butyramide | MLS000735634 | N,N-dimethyl-4-[1-(2-methylpropyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-4-oxidanylidene-butanamide | N,N-dimethyl-4-[1-(2-methylpropyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-4-oxobutanamide | SMR000318867 | cid_16188765
Type:
Small organic molecule
Emp. Form.:
C21H29N3O2
Mol. Mass.:
355.4739
SMILES:
CC(C)CC1N(CCc2c1[nH]c1ccccc21)C(=O)CCC(=O)N(C)C
Structure:
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