Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43642
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43642
Synonyms:
1-(1H-indol-2-ylmethyl)-4-(2-oxanylmethyl)-4-piperidinecarboxylic acid ethyl ester | 1-(1H-indol-2-ylmethyl)-4-(tetrahydropyran-2-ylmethyl)isonipecotic acid ethyl ester | MLS000735864 | SMR000317419 | cid_16192254 | ethyl 1-(1H-indol-2-ylmethyl)-4-(oxan-2-ylmethyl)piperidine-4-carboxylate | ethyl 1-(1H-indol-2-ylmethyl)-4-(tetrahydro-2H-pyran-2-ylmethyl)piperidine-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C23H32N2O3
Mol. Mass.:
384.5118
SMILES:
CCOC(=O)C1(CC2CCCCO2)CCN(Cc2cc3ccccc3[nH]2)CC1
Structure:
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