Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43651
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43651
Synonyms:
3-methoxypropyl-[3-[3-(trifluoromethyl)phenyl]triazolo[1,5-a]quinazolin-5-yl]amine | MLS000686680 | N-(3-methoxypropyl)-3-[3-(trifluoromethyl)phenyl]-5-triazolo[1,5-a]quinazolinamine | N-(3-methoxypropyl)-3-[3-(trifluoromethyl)phenyl]-[1,2,3]triazolo[1,5-a]quinazolin-5-amine | N-(3-methoxypropyl)-3-[3-(trifluoromethyl)phenyl][1,2,3]triazolo[1,5-a]quinazolin-5-amine | N-(3-methoxypropyl)-3-[3-(trifluoromethyl)phenyl]triazolo[1,5-a]quinazolin-5-amine | SMR000339735 | cid_2137472
Type:
Small organic molecule
Emp. Form.:
C20H18F3N5O
Mol. Mass.:
401.385
SMILES:
COCCCNc1nc2c(nnn2c2ccccc12)-c1cccc(c1)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: