Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43652
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>688±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43652
Synonyms:
MLS000706198 | SMR000288250 | [5-amino-3-(4-chlorophenyl)-1,2,4-triazol-1-yl]-(2-thienyl)methanone | [5-amino-3-(4-chlorophenyl)-1,2,4-triazol-1-yl]-thiophen-2-ylmethanone | [5-azanyl-3-(4-chlorophenyl)-1,2,4-triazol-1-yl]-thiophen-2-yl-methanone | cid_828580
Type:
Small organic molecule
Emp. Form.:
C13H9ClN4OS
Mol. Mass.:
304.755
SMILES:
Nc1nc(nn1C(=O)c1cccs1)-c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: