Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43653
Substrate
n/a
Meas. Tech.
Dose response cell-based assay to measure STAT3 activation
IC50
>55700±n/a nM
Citation
 PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43653
Synonyms:
1-[3-(4-nitroanilino)-1-indolyl]ethanone | 1-[3-(4-nitroanilino)indol-1-yl]ethanone | 1-[3-[(4-nitrophenyl)amino]indol-1-yl]ethanone | 1-acetyl-N-(4-nitrophenyl)-1H-indol-3-amine | MLS000724544 | SMR000306137 | cid_12426536
Type:
Small organic molecule
Emp. Form.:
C16H13N3O3
Mol. Mass.:
295.2927
SMILES:
CC(=O)n1cc(Nc2ccc(cc2)[N+]([O-])=O)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: