Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43660
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43660
Synonyms:
2-furfuryl-[5-methyl-2-(p-tolyl)pyrazolo[1,5-a]pyrimidin-7-yl]amine | Furan-2-ylmethyl-(5-methyl-2-p-tolyl-pyrazolo[1,5-a]pyrimidin-7-yl)-amine | MLS000035206 | N-(2-furanylmethyl)-5-methyl-2-(4-methylphenyl)-7-pyrazolo[1,5-a]pyrimidinamine | N-(furan-2-ylmethyl)-5-methyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine | SMR000007915 | cid_653674
Type:
Small organic molecule
Emp. Form.:
C19H18N4O
Mol. Mass.:
318.3724
SMILES:
Cc1ccc(cc1)-c1cc2nc(C)cc(NCc3ccco3)n2n1
Structure:
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