Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM30718
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM30718
Synonyms:
7-(diethylamino)-2-keto-N-(2-pyridyl)chromene-3-carboxamide | 7-(diethylamino)-2-oxidanylidene-N-pyridin-2-yl-chromene-3-carboxamide | 7-(diethylamino)-2-oxo-N-(2-pyridinyl)-1-benzopyran-3-carboxamide | 7-(diethylamino)-2-oxo-N-pyridin-2-ylchromene-3-carboxamide | JMC493759 Compound 3 | MLS000079476 | SMR000039268 | cid_658314
Type:
Small organic molecule
Emp. Form.:
C19H19N3O3
Mol. Mass.:
337.3725
SMILES:
CCN(CC)c1ccc2cc(C(=O)Nc3ccccn3)c(=O)oc2c1
Structure:
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