Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43664
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43664
Synonyms:
5-(4-methoxyanilino)-2-thiophen-2-yl-1,3-oxazole-4-carbonitrile | 5-(4-methoxyanilino)-2-thiophen-2-yl-4-oxazolecarbonitrile | 5-(p-anisidino)-2-(2-thienyl)oxazole-4-carbonitrile | 5-[(4-methoxyphenyl)amino]-2-thiophen-2-yl-1,3-oxazole-4-carbonitrile | MLS000036621 | SMR000041868 | cid_661263
Type:
Small organic molecule
Emp. Form.:
C15H11N3O2S
Mol. Mass.:
297.332
SMILES:
COc1ccc(Nc2oc(nc2C#N)-c2cccs2)cc1
Structure:
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