Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43674
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43674
Synonyms:
MLS000065674 | N-(2,3-dihydro-1H-inden-5-yl)-2-methyl-3-furamide | N-(2,3-dihydro-1H-inden-5-yl)-2-methyl-3-furancarboxamide | N-(2,3-dihydro-1H-inden-5-yl)-2-methyl-furan-3-carboxamide | N-(2,3-dihydro-1H-inden-5-yl)-2-methylfuran-3-carboxamide | N-indan-5-yl-2-methyl-3-furamide | SMR000080326 | cid_1245270
Type:
Small organic molecule
Emp. Form.:
C15H15NO2
Mol. Mass.:
241.2851
SMILES:
Cc1occc1C(=O)Nc1ccc2CCCc2c1
Structure:
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