Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43689
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43689
Synonyms:
MLS000567289 | N-pentyl-4-phenyl-1,3-thiazol-2-amine | N-pentyl-4-phenyl-2-thiazolamine | SMR000153992 | amyl-(4-phenylthiazol-2-yl)amine | cid_2560470
Type:
Small organic molecule
Emp. Form.:
C14H18N2S
Mol. Mass.:
246.371
SMILES:
CCCCCNc1nc(cs1)-c1ccccc1
Structure:
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