Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM34735
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM34735
Synonyms:
1-(4-methoxyphenyl)-3-(6-quinoxalinyl)thiourea | 1-(4-methoxyphenyl)-3-quinoxalin-6-yl-thiourea | 1-(4-methoxyphenyl)-3-quinoxalin-6-ylthiourea | MLS000581626 | N-(4-methoxyphenyl)-N'-6-quinoxalinylthiourea | SMR000200258 | cid_972779
Type:
Small organic molecule
Emp. Form.:
C16H14N4OS
Mol. Mass.:
310.374
SMILES:
COc1ccc(NC(=S)Nc2ccc3nccnc3c2)cc1
Structure:
Search PDB for entries with ligand similarity: