Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43702
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43702
Synonyms:
1-(4-Nitro-benzoyl)-3-pyridin-2-yl-thiourea | 4-nitro-N-(2-pyridylthiocarbamoyl)benzamide | 4-nitro-N-(pyridin-2-ylcarbamothioyl)benzamide | 4-nitro-N-[(2-pyridinylamino)-sulfanylidenemethyl]benzamide | MLS000567023 | SMR000173880 | cid_837855
Type:
Small organic molecule
Emp. Form.:
C13H10N4O3S
Mol. Mass.:
302.309
SMILES:
[O-][N+](=O)c1ccc(cc1)C(=O)NC(=S)Nc1ccccn1
Structure:
Search PDB for entries with ligand similarity: