Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43709
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43709
Synonyms:
MLS000681135 | N-[(3-acetylanilino)-sulfanylidenemethyl]-3-methylbenzamide | N-[(3-acetylphenyl)carbamothioyl]-3-methylbenzamide | N-[(3-acetylphenyl)thiocarbamoyl]-3-methyl-benzamide | N-[(3-ethanoylphenyl)carbamothioyl]-3-methyl-benzamide | N-{[(3-acetylphenyl)amino]carbonothioyl}-3-methylbenzamide | SMR000269386 | cid_833124
Type:
Small organic molecule
Emp. Form.:
C17H16N2O2S
Mol. Mass.:
312.386
SMILES:
CC(=O)c1cccc(NC(=S)NC(=O)c2cccc(C)c2)c1
Structure:
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