Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43730
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43730
Synonyms:
(E)-2-methyl-3-phenyl-N-(1,3-thiazol-2-yl)prop-2-enamide | (E)-2-methyl-3-phenyl-N-(2-thiazolyl)-2-propenamide | (E)-2-methyl-3-phenyl-N-thiazol-2-yl-acrylamide | 2-methyl-3-phenyl-N-1,3-thiazol-2-ylacrylamide | MLS000662493 | SMR000292262 | cid_2189305
Type:
Small organic molecule
Emp. Form.:
C13H12N2OS
Mol. Mass.:
244.312
SMILES:
C\C(=C/c1ccccc1)C(=O)Nc1nccs1
Structure:
Search PDB for entries with ligand similarity: