Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43735
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43735
Synonyms:
2-methyl-N-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]benzamide | 2-methyl-N-[4-(2-methyl-4-thiazolyl)phenyl]benzamide | 2-methyl-N-[4-(2-methylthiazol-4-yl)phenyl]benzamide | MLS000662188 | SMR000293089 | cid_2196790
Type:
Small organic molecule
Emp. Form.:
C18H16N2OS
Mol. Mass.:
308.397
SMILES:
Cc1nc(cs1)-c1ccc(NC(=O)c2ccccc2C)cc1
Structure:
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