Reaction Details Report a problem with these data
Target
Signal transducer and activator of transcription 3 [702-738,740-752]
Ligand
BDBM43740
Substrate
n/a
Meas. Tech.
Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation
EC50
>55700±n/a nM
Citation
 PubChem, PC Dose response counterscreen for STAT1 activators: cell-based high throughput assay to measure STAT3 activation PubChem Bioassay (2008)[AID] 
Target
Name:
Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:
APRF | STAT3 | STAT3_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
5263.93
Organism:
Homo sapiens (Human)
Description:
gi_13272532
Residue:
50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
  
Inhibitor
Name:
BDBM43740
Synonyms:
(phenylmethyl) 4-ethyl-3,5-dimethyl-1H-pyrrole-2-carboxylate | 4-ethyl-3,5-dimethyl-1H-pyrrole-2-carboxylic acid (phenylmethyl) ester | 4-ethyl-3,5-dimethyl-1H-pyrrole-2-carboxylic acid benzyl ester | MLS000688119 | SMR000284272 | benzyl 4-ethyl-3,5-dimethyl-1H-pyrrole-2-carboxylate | cid_563688
Type:
Small organic molecule
Emp. Form.:
C16H19NO2
Mol. Mass.:
257.3276
SMILES:
CCc1c(C)[nH]c(C(=O)OCc2ccccc2)c1C
Structure:
Search PDB for entries with ligand similarity: