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Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM44380
Substrate
n/a
Meas. Tech.
TNAP luminescent HTS assay
IC50
10200±470 nM
Citation
 PubChem, PC TNAP luminescent HTS assay PubChem Bioassay (2008)[AID] 
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM44380
Synonyms:
3-(1-methyl-2-pyrrolyl)-1H-pyrazole-5-carboxylic acid | 3-(1-methylpyrrol-2-yl)-1H-pyrazole-5-carboxylic acid | 5-(1-Methyl-1H-pyrrol-2-yl)-2H-pyrazole-3-carboxylic acid | MLS000027259 | SMR000014951 | cid_644947
Type:
Small organic molecule
Emp. Form.:
C9H9N3O2
Mol. Mass.:
191.1867
SMILES:
Cn1cccc1-c1cc([nH]n1)C(O)=O
Structure:
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