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Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM44402
Substrate
n/a
Meas. Tech.
TNAP luminescent HTS assay
IC50
>100000±0 nM
Citation
 PubChem, PC TNAP luminescent HTS assay PubChem Bioassay (2008)[AID] 
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM44402
Synonyms:
MLS000096194 | N-[2-(dimethylamino)ethyl]-2-(6-keto-3-phenyl-pyridazin-1-yl)acetamide | N-[2-(dimethylamino)ethyl]-2-(6-oxidanylidene-3-phenyl-pyridazin-1-yl)ethanamide | N-[2-(dimethylamino)ethyl]-2-(6-oxo-3-phenyl-1-pyridazinyl)acetamide | N-[2-(dimethylamino)ethyl]-2-(6-oxo-3-phenylpyridazin-1(6H)-yl)acetamide | N-[2-(dimethylamino)ethyl]-2-(6-oxo-3-phenylpyridazin-1-yl)acetamide | SMR000032142 | cid_3235832
Type:
Small organic molecule
Emp. Form.:
C16H20N4O2
Mol. Mass.:
300.3556
SMILES:
CN(C)CCNC(=O)Cn1nc(ccc1=O)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: