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Target
Alkaline phosphatase, tissue-nonspecific isozyme
Ligand
BDBM44409
Substrate
n/a
Meas. Tech.
TNAP luminescent HTS assay
IC50
>100000±0 nM
Citation
 PubChem, PC TNAP luminescent HTS assay PubChem Bioassay (2008)[AID] 
Target
Name:
Alkaline phosphatase, tissue-nonspecific isozyme
Synonyms:
ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor
Type:
PROTEIN
Mol. Mass.:
57306.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448917
Residue:
524
Sequence:
MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
  
Inhibitor
Name:
BDBM44409
Synonyms:
1-(2-fluorophenyl)-4-{[4-(1H-pyrrol-1-yl)phenyl]acetyl}piperazine | 1-[4-(2-fluorophenyl)-1-piperazinyl]-2-[4-(1-pyrrolyl)phenyl]ethanone | 1-[4-(2-fluorophenyl)piperazin-1-yl]-2-(4-pyrrol-1-ylphenyl)ethanone | 1-[4-(2-fluorophenyl)piperazino]-2-(4-pyrrol-1-ylphenyl)ethanone | MLS000047177 | SMR000033188 | cid_3243883
Type:
Small organic molecule
Emp. Form.:
C22H22FN3O
Mol. Mass.:
363.428
SMILES:
Fc1ccccc1N1CCN(CC1)C(=O)Cc1ccc(cc1)-n1cccc1
Structure:
Search PDB for entries with ligand similarity: