Reaction Details Report a problem with these data
Target
Protein Rev [8-24]
Ligand
BDBM44542
Substrate
n/a
Meas. Tech.
Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction)
IC50
>79370±n/a nM
Citation
 PubChem, PC Dose response biochemical assay to identify inhibitors of the HIV Rev - RRE RNA interaction (disruption of protein-RNA interaction) PubChem Bioassay (2007)[AID] 
Target
Name:
Protein Rev [8-24]
Synonyms:
Chain B, Rna Aptamer Complexed With Hiv-1 Rev Peptide, Nmr, 7 Structures | REV_HV1W2 | rev
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2446.81
Organism:
Human immunodeficiency virus 1
Description:
gi_253722402
Residue:
17
Sequence:
TRQARRNRRRRWRERQR
  
Inhibitor
Name:
BDBM44542
Synonyms:
(1-bicyclo[2.2.1]hept-2-ylethyl)[4-(dimethylamino)benzyl]amine hydrochloride | 4-[[1-(3-bicyclo[2.2.1]heptanyl)ethylamino]methyl]-N,N-dimethyl-aniline;hydrochloride | 4-[[1-(3-bicyclo[2.2.1]heptanyl)ethylamino]methyl]-N,N-dimethylaniline;hydrochloride | MLS000537385 | SMR000143823 | cid_2967205 | dimethyl-[4-[[1-(2-norbornyl)ethylamino]methyl]phenyl]amine;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C18H28N2
Mol. Mass.:
272.4283
SMILES:
[H]C12CCC([H])(C1)C(C2)C(C)NCc1ccc(cc1)N(C)C |TLB:9:7:6:3.2|
Structure:
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